Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21066360 | 0.78 | MAPT (0.49) | KDM4ELMNA | |
| SCHEMBL11094667 | 0.78 | KDM4E (0.41) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11123547 | 0.73 | LMNA (0.51) | PIM1PIM2LMNAAKR1B1PTGS2 | |
| SCHEMBL1705418 | 0.72 | KDM4E (0.42) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31208289 | 0.72 | KDM4E (0.42) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| Methane SCHEMBL11094670 | 0.71 | HDAC3 (0.43) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10897276 | 0.69 | AKR1B1 (0.51) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19899576 | 0.69 | AGPAT2 (0.42) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19899503 | 0.69 | HDAC3 (0.44) | KDM4EHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3080166 | 0.69 | AGPAT2 (0.45) | KDM4EHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | KDM4E 3731/4885HDAC3 2255/4885HDAC1 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.