SCHEMBL2106679

SCHEMBL2106679

N#Cc1ccccc1-c1c(Br)[c]c(Br)cc1S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.32
PTPN5 P54829 1/20 0.32
SLC22A12 Q96S37 1/20 0.31
PDK2 Q15119 1/20 0.30
NR1H3 Q13133 1/20 0.30
USP8 P40818 1/20 0.30
USP7 Q93009 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2104604 0.85 CA1 (0.30)
SCHEMBL2102801 0.84
SCHEMBL2105608 0.83 SDHB (0.32)
SCHEMBL2103581 0.83
SCHEMBL2106570 0.83
SCHEMBL12003750 0.82 HSD11B1 (0.31) HSD11B1
SCHEMBL2104893 0.80 HSD11B1 (0.33) HSD11B1PTPN5SLC22A12
SCHEMBL2106351 0.80
SCHEMBL2106680 0.79 EPAS1 (0.37) PTPN5SLC22A12PDK2
SCHEMBL2105992 0.79 MMP1 (0.35) HSD11B1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8563736-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-8163804-B2 Composition for preventing harmful organisms MITSUI CHEMICALS, INC. (JP) 2012-04-24 US disclosed