Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.57 |
| ▸ | CYCS | P99999 | 3/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30092778 | 0.96 | TOP1 (0.60) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL10592809 | 0.96 | TOP1 (0.60) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28346272 | 0.95 | TOP1 (0.58) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28369968 | 0.95 | TOP1 (0.58) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL29437853 | 0.95 | TOP1 (0.58) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL28494180 | 0.87 | TOP1 (0.55) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL23014694 | 0.82 | TOP1 (0.77) | TOP1CYCSTERTENPP2ABCG2 | |
| SCHEMBL9588215 | 0.82 | TOP1 (0.48) | TOP1CYCSTERTENPP2 | |
| SCHEMBL2240990 | 0.81 | TOP1 (0.60) | TOP1CYCSTERTENPP2 | |
| SCHEMBL16604344 | 0.79 | TOP1 (0.50) | TOP1CYCSTERTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529332-B2 | Corroles for treating poxvirus infection | UNIVERSITE DE BOURGOGNE (FR) | 2022-12-20 | — | — | US | disclosed |
| US-20210369671-A1 | CORROLES FOR TREATING HUMAN CYTOMEGALOVIRUS INFECTIONS | UNIVERSITE DE BOURGOGNE (FR) | 2021-12-02 | — | — | US | disclosed |
| US-20210169853-A1 | CORROLES FOR TREATING POXVIRUS INFECTION | UNIVERSITE DE BOURGOGNE (FR) | 2021-06-10 | — | — | US | disclosed |
| EP-3492078-A1 | CORROLES FOR TREATING HUMAN CYTOMEGALOVIRUS INFECTIONS | Université de Bourgogne (FR) | 2019-06-05 | — | — | EP | disclosed |
| EP-3492079-A1 | CORROLES FOR TREATING POXVIRUS INFECTION | Université de Bourgogne (FR) | 2019-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529332-B2 | Corroles for treating poxvirus infection | VAC14, PPOX, GPX4 | TOP1 145/4885CYCS 184/4885TERT 1356/4885 |
| US-20210169853-A1 | CORROLES FOR TREATING POXVIRUS INFECTION | VAC14, PPOX, GPX4 | TOP1 145/4885CYCS 184/4885TERT 1356/4885 |
| US-20210369671-A1 | CORROLES FOR TREATING HUMAN CYTOMEGALOVIRUS INFECTIONS | MGMT, RPL35, RPL5 | TOP1 53/4885CYCS 376/4885TERT 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.