Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 11/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.45 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687290 | 0.80 | GAB1 (0.45) | ACLYGAB1 | |
| SCHEMBL4316537 | 0.79 | GAB1 (0.44) | GAB1 | |
| SCHEMBL3556126 | 0.77 | MEN1 (0.47) | ACLYGAB1METAP2 | |
| SCHEMBL3552834 | 0.75 | MEN1 (0.45) | ACLYGAB1METAP2 | |
| SCHEMBL3557735 | 0.74 | SLC16A3 (0.45) | ACLYGAB1METAP2 | |
| SCHEMBL15880546 | 0.72 | CA2 (0.52) | GAB1 | |
| SCHEMBL14087505 | 0.71 | GAB1 (0.51) | GAB1 | |
| SCHEMBL3557484 | 0.70 | HDAC1 (0.45) | ACLYMCL1GAB1METAP2 | |
| SCHEMBL3558197 | 0.70 | SLC16A3 (0.60) | ACLYGAB1 | |
| SCHEMBL21999779 | 0.70 | ACLY (1.00) | ACLYMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |