Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 11/20 | 0.84 |
| ▸ | CA1 | P00915 | 3/20 | 0.84 |
| ▸ | CA2 | P00918 | 3/20 | 0.84 |
| ▸ | CA9 | Q16790 | 3/20 | 0.84 |
| ▸ | ESR1 | P03372 | 2/20 | 0.84 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.84 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.84 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.84 |
| ▸ | CA4 | P22748 | 1/20 | 0.84 |
| ▸ | CA6 | P23280 | 1/20 | 0.84 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531381 | 0.92 | STS (0.82) | STSCA1CA2CA9ESR1 | |
| SCHEMBL8034430 | 0.92 | STS (0.82) | STSCA1CA2CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL4812138 | 0.91 | KDM4E (0.96) | STSCA1CA2CA9ESR1 | |
| SCHEMBL21034361 | 0.91 | STS (0.80) | STSCA1CA2CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL22846 | 0.91 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL2296097 | 0.91 | KDM4E (0.96) | STSCA1CA2CA9ESR1 | |
| Emate SCHEMBL6370815 | 0.91 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| Emate SCHEMBL14548146 | 0.91 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL12920398 | 0.91 | STS (1.00) | STSCA1CA2CA9ESR1 | |
| Emate SCHEMBL10062721 | 0.91 | STS (1.00) | STSCA1CA2CA9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116656771-A | Detection method for judging whether test object is SLC transporter substrate or inhibitor | 江苏鼎泰药物研究(集团)股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-1780634-A | Methods and compositions using gonadotropin hormone releasing hormone | DEBIOPHARM SA (CH) | 2006-05-31 | — | — | CN | claimed |
| CN-116656771-A | Detection method for judging whether test object is SLC transporter substrate or inhibitor | 江苏鼎泰药物研究(集团)股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-218280757-U | Filter equipment is used in preparation of estrone sulfate piperazine | 上海高准医药有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-114306388-A | Deer fetus freeze-dried decoction pieces and preparation method thereof | 江西纳弗堂制药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| CN-101316856-A | Prodrugs of ER-beta-selective substances method for production thereof and pharmaceutical compositions comprising the same | SCHERING AG (DE) | 2008-12-03 | — | — | CN | disclosed |
| CN-1780634-A | Methods and compositions using gonadotropin hormone releasing hormone | DEBIOPHARM SA (CH) | 2006-05-31 | — | — | CN | disclosed |
| CN-1148180-C | Compounds for treatment of estrogen-dependent illnesses and methods for making and using same | ������˹�ضſϴ�ѧ | 2004-05-05 | — | — | CN | disclosed |
| CN-1326345-A | Compounds for treatment of estrogen-dependent illnesses and methods for making and using same | DUQUESNE UNIV OF THE HOLY GHOS (US) | 2001-12-12 | — | — | CN | disclosed |