Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 16/20 | 1.00 |
| ▸ | CA2 | P00918 | 4/20 | 1.00 |
| ▸ | CA1 | P00915 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | ESR1 | P03372 | 2/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 2/20 | 1.00 |
| ▸ | CA4 | P22748 | 1/20 | 1.00 |
| ▸ | CA6 | P23280 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.80 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emate SCHEMBL305660 | 1.00 | STS (1.00) | STSCA2CA1CA9ESR1 | |
| Emate SCHEMBL14548146 | 1.00 | STS (1.00) | STSCA2CA1CA9ESR1 | |
| Emate SCHEMBL29406834 | 1.00 | STS (1.00) | STSCA2CA1CA9ESR1 | |
| Emate SCHEMBL10062721 | 1.00 | STS (1.00) | STSCA2CA1CA9ESR1 | |
| SCHEMBL21067318 | 0.91 | STS (0.84) | STSCA2CA1CA9ESR1 | |
| Emate SCHEMBL7164522 | 0.91 | STS (0.86) | STSCA2CA1CA9ESR1 | |
| SCHEMBL17531381 | 0.90 | STS (0.82) | STSCA2CA1CA9ESR1 | |
| SCHEMBL8034430 | 0.90 | STS (0.82) | STSCA2CA1CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL2296097 | 0.89 | KDM4E (0.96) | STSCA2CA1CA9ESR1 | |
| Estrone Sulfuric Acid SCHEMBL22846 | 0.89 | STS (1.00) | STSCA2CA1CA9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841548-B2 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | SCHERING AG (DE) | 2005-01-11 | — | — | US | claimed |
| EP-0775155-B1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AG (DE) | 2004-05-06 | — | — | EP | claimed |
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | STERIX LIMITED (GB) | 2002-05-23 | — | — | US | claimed |
| CN-121652368-A | Water-based polyurethane-polyurea emulsion and preparation method thereof | 广东普赛达材料科技股份有限公司 | 2026-03-13 | — | — | CN | disclosed |
| US-20200163913-A1 | CA-4 Antitumour Drug, Synthesis Method and Use Thereof | SHANGHAI HUALI BIOMEDICAL CO., LTD. (CN) | 2020-05-28 | — | — | US | disclosed |
| WO-2019020016-A1 | CA-4 ANTITUMOUR DRUG, SYNTHESIS METHOD AND USE THEREOF | 上海华理生物医药股份有限公司 | 2019-01-31 | — | — | WO | disclosed |
| EP-2484351-B1 | Use of steroid sulfatase inhibitors for the treatment of preterm labor | PREGLEM SA (CH) | 2016-02-24 | — | — | EP | disclosed |
| US-20150065470-A1 | Steroid Sulfatase Inhibitor Regimen for the Treatment of Endometriosis | PREGLEM SA (CH) | 2015-03-05 | — | — | US | disclosed |
| US-20150065470-A1 | Steroid Sulfatase Inhibitor Regimen for the Treatment of Endometriosis | PREGLEM SA (CH) | 2015-03-05 | — | — | US | disclosed |
| WO-2013150471-A1 | STEROID SULFATASE INHIBITOR REGIMEN FOR THE TREATMENT OF ENDOMETRIOSIS | PREGLEM SA (CH) | 2013-10-10 | — | — | WO | disclosed |
| EP-2647378-A1 | Steroid sulfatase inhibitor regimen for the treatment of endometriosis | PregLem S.A. (CH) | 2013-10-09 | — | — | EP | disclosed |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2007-05-17 | — | — | US | disclosed |
| US-20070105886-A1 | Steroidal compounds for inhibiting steroid sulphatase | RICHTER GEDEON NYRT. (HU) | 2007-05-10 | — | — | US | disclosed |
| US-20070021492-A1 | e.g. sulfamic acid, 1,2,3,4-tetrahydro-dibenzothiophene-7-yl-1,1-dioxide ester; estrogen-dependent diseases | LABORATOIRE THERAMEX (MC) | 2007-01-25 | — | — | US | disclosed |
| US-20070021492-A1 | e.g. sulfamic acid, 1,2,3,4-tetrahydro-dibenzothiophene-7-yl-1,1-dioxide ester; estrogen-dependent diseases | LABORATOIRE THERAMEX (MC) | 2007-01-25 | — | — | US | disclosed |
| US-6841548-B2 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | SCHERING AG (DE) | 2005-01-11 | — | — | US | disclosed |
| EP-0775156-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ESTRA-1,3,5(10)-TRIENE DERIVATIVES | JENAPHARM GMBH (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6569844-B1 | Hormonal contraception and hormon replacement therapy with low hepatic estrogenity | JENAPHARM GMBH & CO., KG (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | STERIX LIMITED (GB) | 2002-05-23 | — | — | US | disclosed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061868-A1 | Pharmaceutical preparations containing estra-1,3,5(10)-triene derivatives | ESRRA, ESR2, CYP19A1 | STS 124/4885CA2 4144/4885CA1 3531/4885 |
| US-20070021492-A1 | e.g. sulfamic acid, 1,2,3,4-tetrahydro-dibenzothiophene-7-yl-1,1-dioxide ester; estrogen-dependent diseases | SULT1E1, SULT1A1, SULT2A1 | STS 7/4885CA2 623/4885CA1 267/4885 |
| US-20150065470-A1 | Steroid Sulfatase Inhibitor Regimen for the Treatment of Endometriosis | SULT2A1, SULT1E1, STS | STS 3/4885CA2 988/4885CA1 685/4885 |
| US-20070105886-A1 | Steroidal compounds for inhibiting steroid sulphatase | STS, NR5A1, CYP21A2 | STS 1/4885CA2 1367/4885CA1 630/4885 |
| US-20070112009-A1 | 1-N-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them | H1-0, H1-5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | STS 4396/4885CA2 2378/4885CA1 4252/4885 |
| US-20200163913-A1 | CA-4 Antitumour Drug, Synthesis Method and Use Thereof | CA4, CA14, CA6 | STS 105/4885CA2 5/4885CA1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.