Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 1.00 |
| ▸ | NUDT1 | P36639 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597858 | 0.90 | BACE1 (0.81) | BACE1NUDT1MAPK1TAAR1KDM4E | |
| SCHEMBL10596917 | 0.87 | NUDT1 (0.77) | BACE1NUDT1ALOX15HSP90AA1THRB | |
| SCHEMBL10595253 | 0.87 | NUDT1 (0.77) | BACE1NUDT1ALOX15HSP90AA1THRB | |
| SCHEMBL28265234 | 0.85 | NUDT1 (0.74) | BACE1NUDT1ALOX15HSP90AA1THRB | |
| SCHEMBL3812723 | 0.85 | BACE1 (0.74) | BACE1NUDT1KDM4EMAPTALDH1A1 | |
| SCHEMBL10594734 | 0.85 | NUDT1 (0.74) | BACE1NUDT1ALOX15HSP90AA1THRB | |
| SCHEMBL917277 | 0.84 | NUDT1 (0.72) | BACE1NUDT1DRD2DRD1DRD4 | |
| SCHEMBL16499437 | 0.83 | BACE1 (0.71) | BACE1NUDT1MAPK1TAAR1KDM4E | |
| SCHEMBL7182409 | 0.83 | NUDT1 (0.71) | BACE1NUDT1KDM4EMAPTGAA | |
| SCHEMBL2909089 | 0.83 | BACE1 (0.70) | BACE1NUDT1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |