SCHEMBL2909089

SCHEMBL2909089

OCCCc1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.70

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.70
NUDT1 P36639 1/20 0.70
HSP90AA1 P07900 1/20 0.47
IGF1R P08069 5/20 0.42
ALOX15 P16050 5/20 0.42
BCHE P06276 3/20 0.42
ACHE P22303 2/20 0.42
THRB P10828 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ALOX5 P09917 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
THRA P10827 2/20 0.38
CA2 P00918 1/20 0.36
ACMSD Q8TDX5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10595253 0.92 NUDT1 (0.77) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL10596917 0.92 NUDT1 (0.77) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL3812723 0.90 BACE1 (0.74) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL28265234 0.90 NUDT1 (0.74) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL10594734 0.90 NUDT1 (0.74) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL10597858 0.89 BACE1 (0.81) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL5682327 0.86 NUDT1 (0.68) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL5680382 0.85 NUDT1 (0.67) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL11596345 0.84 NUDT1 (0.66) BACE1NUDT1HSP90AA1IGF1RALOX15
SCHEMBL5189846 0.84 NUDT1 (0.65) BACE1NUDT1ACHEKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
CN-1572795-A Process for producing phosphite SUMITOMO CHEMICAL CO (JP) 2005-02-02 CN disclosed
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 BACE1 4580/4885NUDT1 659/4885HSP90AA1 2708/4885
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 BACE1 3727/4885NUDT1 1593/4885HSP90AA1 4676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.