Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409879 | 0.80 | ADRA2A (0.49) | MAPK1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL2762379 | 0.75 | MAPK1 (0.58) | MAPK1LMNAHTTSLC6A4LRRK2 | |
| SCHEMBL6135165 | 0.74 | KDM4E (0.48) | MAPK1LMNAHTTSLC6A4HTR2A | |
| SCHEMBL6825718 | 0.73 | RAB9A (0.46) | MAPK1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6652201 | 0.73 | TSHR (0.54) | PDE4BLMNAHTTPTGESKDM4E | |
| SCHEMBL1586713 | 0.72 | CA12 (0.63) | PDE4BMAPK1LMNAHTTPTGES | |
| SCHEMBL8212052 | 0.72 | EP300 (0.45) | PDE4BHTTPTGESKDM4ETSHR | |
| SCHEMBL8203218 | 0.70 | MAPT (0.48) | PDE4BMAPK1LMNAKCNH2PTGES | |
| SCHEMBL7788841 | 0.70 | MAPT (0.55) | ADRA2ALMNAHTTSLC6A3KDM4E | |
| SCHEMBL16692664 | 0.70 | TSHR (0.66) | PDE4BMAPK1LMNAHTTPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |