Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067362 | 0.80 | PDE4B (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9781407 | 0.77 | SYK (0.50) | ADRA2AADRA2BADRA2CSYKCYP3A4 | |
| SCHEMBL3785602 | 0.77 | MAPT (0.59) | SYKCYP3A4KDM4EALDH1A1MAPK1 | |
| SCHEMBL6408609 | 0.76 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6825718 | 0.76 | RAB9A (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL3510154 | 0.75 | HTR2A (0.41) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7572810 | 0.75 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL13138528 | 0.74 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL14439923 | 0.74 | SYK (0.50) | SYKCYP3A4KDM4EALDH1A1MAPK1 | |
| SCHEMBL1663657 | 0.74 | GAA (0.61) | SYKCYP3A4KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |
| US-6921770-B2 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-07-26 | — | — | US | disclosed |
| EP-1311160-A4 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INST SCI & TECH (KR) | 2004-04-21 | — | — | EP | disclosed |
| US-6710077-B1 | CONTRACEPTIVE VEHICLE COMPRISING A MEANS FOR BIRTH CONTROL AND AN HIV-PROTECTIVE | UNIROYAL CHEMICAL COMPANY, INC. | 2004-03-23 | — | — | US | disclosed |
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-10-30 | — | — | US | disclosed |
| EP-1311160-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-05-21 | — | — | EP | disclosed |
| EP-0910366-B1 | USE OF THIOCARBOXANILIDE DERIVATIVES FOR THE PREPARATION OF A MEDICAMENT FOR PREVENTING THE TRANSMISSION OF HIV TO UNINFECTED CELLS AND CONTRACEPTIVE COMPOSITIONS COMPRISING THE SAID DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0874839-B1 | FURAN- AND THIOPHENECARBOTHIOAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE REPLICATION OF HIV-1 AND HIV-1 MUTANTS | UNIROYAL CHEM CO INC (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2002013611-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-02-21 | — | — | WO | disclosed |
| EP-0910366-A1 | USE OF THIOCARBOXANILIDE DERIVATIVES FOR THE PREPARATION OF A MEDICAMENT FOR PREVENTING THE TRANSMISSION OF HIV TO UNINFECTED CELLS AND CONTRACEPTIVE COMPOSITIONS COMPRISING THE SAID DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0874839-A1 | FURAN- AND THIOPHENECARBOTHIOAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE REPLICATION OF HIV-1 AND HIV-1 MUTANTS | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5696151-A | Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997045116-A1 | USE OF THIOCARBOXANILIDE DERIVATIVES FOR THE PREPARATION OF A MEDICAMENT FOR PREVENTING THE TRANSMISSION OF HIV TO UNINFECTED CELLS AND CONTRACEPTIVE COMPOSITIONS COMPRISING THE SAID DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
| WO-1997019940-A1 | FURAN- AND THIOPHENECARBOTHIOAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE REPLICATION OF HIV-1 AND HIV-1 MUTANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | TYR, SYPL1, SSBP1 | ADRA2A 3359/4885ADRA2B 3497/4885ADRA2C 3396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.