Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 1.00 |
| ▸ | XDH | P47989 | 5/20 | 0.64 |
| ▸ | CTSA | P10619 | 4/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.44 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | CASP5 | P51878 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27986244 | 0.78 | XDH (1.00) | CASP3XDHCTSAMKNK1MKNK2 | |
| SCHEMBL10277099 | 0.72 | CASP3 (0.57) | CASP3CASP1CASP2CASP4CASP5 | |
| SCHEMBL17254443 | 0.71 | MKNK1 (0.68) | XDHMKNK1MKNK2 | |
| SCHEMBL28125494 | 0.69 | XDH (0.61) | CASP3XDHMKNK1MKNK2 | |
| SCHEMBL27986242 | 0.69 | MKNK1 (0.87) | CASP3XDHMKNK1MKNK2 | |
| SCHEMBL27986248 | 0.68 | XDH (0.60) | CASP3XDHMKNK1MKNK2 | |
| SCHEMBL31710514 | 0.68 | MKNK1 (0.64) | CASP3XDHMKNK1MKNK2 | |
| SCHEMBL15330383 | 0.68 | MKNK1 (0.64) | CASP3XDHMKNK1MKNK2 | |
| SCHEMBL15637147 | 0.68 | CTSA (1.00) | CTSA | |
| SCHEMBL12190898 | 0.66 | XDH (0.77) | CASP3XDHCTSAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |