Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CTSA | P10619 | 3/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.46 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27986244 | 0.87 | XDH (1.00) | XDHCASP3CTSAMKNK1MKNK2 | |
| SCHEMBL12190887 | 0.84 | ROCK2 (0.61) | XDHCTSAALDH1A1KAT6AROCK2 | |
| SCHEMBL12190909 | 0.82 | XDH (0.54) | XDHSCN10AALDH1A1ROCK2 | |
| SCHEMBL12190842 | 0.81 | XDH (0.63) | XDHCASP3CTSAMKNK1MKNK2 | |
| SCHEMBL13932937 | 0.81 | XDH (0.64) | XDHCASP3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL25002964 | 0.80 | CYP11B2 (0.63) | XDHMKNK1MKNK2ALDH1A1CYP3A4 | |
| SCHEMBL12190884 | 0.75 | CCNC (0.62) | SCN10AKAT6ADYRK1AKCNH2 | |
| SCHEMBL14573319 | 0.75 | CHRNA7 (0.70) | XDHCTSASCN10AKAT6AKCNH2 | |
| SCHEMBL12190998 | 0.75 | XDH (0.59) | XDHALDH1A1EIF2S1EIF2AK3CYP3A4 | |
| SCHEMBL163588 | 0.75 | MLYCD (0.61) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030336-B2 | Nicotinamide-based kinase inhibitors | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2011-10-04 | — | — | US | disclosed |
| US-8030336-B2 | Nicotinamide-based kinase inhibitors | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2011-10-04 | — | — | US | disclosed |
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | CYTOPIA PTY LTD (AU) | 2007-03-15 | — | — | US | disclosed |
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | CYTOPIA PTY LTD (AU) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | NADK, NAMPT, PDXK | XDH 278/4885CASP3 2845/4885CTSA 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.