SCHEMBL21067434

SCHEMBL21067434

c1c(NC2CCCCO2)sc2c1CCOC2

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5449006 0.69 TP53 (0.40) RAB9ASMN1; SMN2
SCHEMBL7854135 0.68 PTPN1 (0.58)
SCHEMBL21412261 0.64
SCHEMBL5455584 0.63 LIMK1 (0.38)
SCHEMBL14930416 0.63 PNMT (0.43) RAB9A
SCHEMBL5741512 0.62 PIK3CA (0.37) RAB9ASMN1; SMN2
SCHEMBL15194473 0.62 PKM (0.40) RAB9ASMN1; SMN2
SCHEMBL5741968 0.61 ALDH1A1 (0.41) RAB9A
SCHEMBL19441931 0.61 KCNH2 (0.35)
SCHEMBL7736354 0.60 KDM4E (0.39) RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed