SCHEMBL21067647

SCHEMBL21067647

OCCCCC(CCO)CCCCO

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
THRB P10828 1/20 0.33
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8329623 0.97 LMNA (0.42) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL6577653 0.90 THRB (0.35) LMNASMN1; SMN2ALDH1A1TSHRTHRB
SCHEMBL6925076 0.90 LMNA (0.46) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL9702342 0.90 LMNA (0.46) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL2451368 0.88 LMNA (0.52) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL14830612 0.87 GSR (0.33) LMNAALDH1A1TSHR
SCHEMBL4850725 0.87 LMNA (0.36) LMNAALDH1A1TSHRHSD17B10MEN1
SCHEMBL8997997 0.87 LMNA (0.46) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL8072510 0.85 LMNA (0.56) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10
SCHEMBL6903763 0.85 LMNA (0.56) LMNASMN1; SMN2ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844431-A Thermoplastic polyurethane adhesive, preparation method and application thereof 万华化学集团股份有限公司 2024-04-09 CN claimed
CN-114316197-B Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof 万华化学集团股份有限公司 2023-07-14 CN claimed
CN-114316197-A Low-polarity high-heat-resistance thermoplastic polyurethane adhesive and application thereof 万华化学集团股份有限公司 2022-04-12 CN claimed
CN-117844431-A Thermoplastic polyurethane adhesive, preparation method and application thereof 万华化学集团股份有限公司 2024-04-09 CN disclosed
CN-114316197-B Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof 万华化学集团股份有限公司 2023-07-14 CN disclosed
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
CN-114316197-A Low-polarity high-heat-resistance thermoplastic polyurethane adhesive and application thereof 万华化学集团股份有限公司 2022-04-12 CN disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed