Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440890 | 0.95 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1099125 | 0.95 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL308119 | 0.92 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9156073 | 0.92 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL17526930 | 0.92 | ALDH1A1 (0.43) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1433752 | 0.92 | LMNA (0.48) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16548258 | 0.90 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL16897039 | 0.90 | ALDH1A1 (0.52) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL17526611 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL17526745 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489630-A | BLENDS OF POLY(ALKYLENE OXIDE)AMINE-EPOXY ADDUCT AND POLYEPOXIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1996-02-06 | — | — | US | disclosed |