Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.93 |
| ▸ | NOS2 | P35228 | 3/20 | 0.93 |
| ▸ | NOS1 | P29475 | 2/20 | 0.93 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195096 | 0.68 | NOS2 (0.80) | NOS3NOS2NOS1TAAR1 | |
| SCHEMBL8214849 | 0.66 | NOS3 (1.00) | NOS3NOS2NOS1TAAR1 | |
| SCHEMBL8218521 | 0.66 | NOS3 (0.70) | NOS3NOS2NOS1TAAR1 | |
| SCHEMBL8186392 | 0.65 | NOS2 (0.85) | NOS3NOS2NOS1TAAR1 | |
| SCHEMBL17585079 | 0.62 | HRH3 (0.54) | NOS3NOS2NOS1HRH3ADRA2A | |
| Hydrochloric Acid SCHEMBL29950499 | 0.62 | HRH3 (0.47) | NOS3NOS2NOS1HRH3ADRA2A | |
| Hydrochloric Acid SCHEMBL27173151 | 0.62 | HRH3 (0.47) | NOS3NOS2NOS1HRH3ADRA2A | |
| SCHEMBL12895388 | 0.61 | HRH3 (0.61) | HRH3ADRA2AADRA2BADRA2CPNMT | |
| SCHEMBL4719681 | 0.61 | HRH3 (0.61) | HRH3ADRA2AADRA2BADRA2CPNMT | |
| SCHEMBL17585078 | 0.60 | HRH3 (0.58) | NOS3NOS2NOS1HRH3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |