SCHEMBL21067674

SCHEMBL21067674

CC(C)C[C@@H](N)C(=O)N(Cc1ccc(C(=N)N)cc1)C(=O)[C@@H]1CCCN1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F2 P00734 19/20 0.39
MASP2 O00187 5/20 0.37
SCN4A P35499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27544516 0.85 CTSC (0.41) F2MASP2
Hydrochloric Acid SCHEMBL27584408 0.85 F2 (0.41) F2MASP2
Hydrochloric Acid SCHEMBL27602241 0.84 SCN4A (0.40) F2MASP2SCN4A
SCHEMBL21067306 0.80 GHSR (0.49) SCN4A
SCHEMBL27456282 0.75 F2 (0.47) F2MASP2
SCHEMBL27469816 0.75 F2 (0.45) F2MASP2
SCHEMBL1369574 0.75 SLC7A5 (0.35) SCN4A
SCHEMBL23752340 0.75 F2 (0.44) F2
SCHEMBL23752610 0.75 F2 (0.44) F2
Hydrochloric Acid SCHEMBL27763761 0.75 F2 (0.47) F2MASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed