Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 17/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067747 | 0.87 | GHSR (0.49) | GHSR | |
| SCHEMBL21067852 | 0.86 | GHSR (0.44) | GHSRALDH1A1GAAL3MBTL1SCN4A | |
| SCHEMBL21067674 | 0.80 | F2 (0.39) | SCN4A | |
| SCHEMBL21067717 | 0.78 | GHSR (0.49) | GHSRSLC6A2SLC6A4SLC6A3SCN4A | |
| SCHEMBL21067757 | 0.76 | CTSC (0.47) | GHSRSCN4A | |
| SCHEMBL21067420 | 0.76 | DPP4 (0.43) | GHSRSLC6A2SLC6A3SCN4A | |
| SCHEMBL1369574 | 0.74 | SLC7A5 (0.35) | SCN4A | |
| SCHEMBL27544516 | 0.69 | CTSC (0.41) | GHSR | |
| SCHEMBL10791037 | 0.69 | CTSC (0.47) | GHSRSCN4A | |
| Hydrochloric Acid SCHEMBL27584408 | 0.69 | F2 (0.41) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |