SCHEMBL1369574

SCHEMBL1369574

CC(C)CC(N)C(=O)N(CC(=O)O)C(=O)C1CCCN1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.35
SCN4A P35499 1/20 0.34
DPP4 P27487 3/20 0.32
DPP7 Q9UHL4 2/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
PRCP P42785 1/20 0.31
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16620345 0.88 SCN4A (0.38) SCN4ADPP7PRCPNOS2
SCHEMBL27740316 0.85 SCN4A (0.33) SCN4ANOS2
SCHEMBL2952396 0.81 DPP4 (0.35) SCN4ADPP4DPP7DPP8DPP9
SCHEMBL10793329 0.81 GSR (0.38) SCN4ADPP4DPP7DPP8DPP9
SCHEMBL3359438 0.79 SCN4A (0.42) SCN4ADPP4DPP7DPP8DPP9
SCHEMBL10791037 0.79 CTSC (0.47) SLC7A5SCN4ADPP4DPP7DPP8
SCHEMBL8720607 0.77 SLC7A5 (0.33) SLC7A5SCN4ASLC1A3SLC1A2
SCHEMBL11287698 0.76 SCN4A (0.36) SCN4A
SCHEMBL21067674 0.75 F2 (0.39) SCN4A
SCHEMBL21067306 0.74 GHSR (0.49) SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0142231-B1 PROCESS FOR PRODUCING SEQUENTIAL POLYAMINO ACID RESIN NITTO BOSEKI CO., LTD. (JP) 1987-11-11 EP claimed
EP-0142231-A1 Process for producing sequential polyamino acid resin NITTO BOSEKI CO., LTD. (JP) 1985-05-22 EP claimed
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 EP disclosed
CN-103665170-A Peptide therapeutic conjugates and uses thereof ANGIOCHEM INC 2014-03-26 CN disclosed
CN-102348723-A Peptide therapeutic agent conjugates and uses thereof ANGIOCHEM INC 2012-02-08 CN disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 WO disclosed
US-4596819-A Antidepressive agents WARNER-LAMBERT COMPANY (US) 1986-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 SLC7A5 102/4885SCN4A 2143/4885DPP4 302/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 SLC7A5 102/4885SCN4A 2143/4885DPP4 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.