SCHEMBL21067747

SCHEMBL21067747

N[C@H](Cc1ccccc1)C(=O)N(Cc1cccc(Cl)c1)C(=O)[C@@H]1CCCN1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 15/20 0.49
CTSC P53634 1/20 0.41
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067757 0.90 CTSC (0.47) GHSRCTSC
SCHEMBL21067420 0.88 DPP4 (0.43) GHSRCTSC
SCHEMBL21067717 0.88 GHSR (0.49) GHSRCTSC
SCHEMBL21067306 0.87 GHSR (0.49) GHSR
SCHEMBL21067852 0.87 GHSR (0.44) GHSR
SCHEMBL10791037 0.82 CTSC (0.47) GHSRCTSC
SCHEMBL27544516 0.82 CTSC (0.41) GHSRCTSCF2
Hydrochloric Acid SCHEMBL27584408 0.81 F2 (0.41) GHSRCTSCF2
SCHEMBL27394991 0.74 SCN4A (0.48) GHSRCTSC
Dl-Phenylalanine SCHEMBL2478801 0.71 SLC7A5 (0.59) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed