Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 10/20 | 0.73 |
| ▸ | MMP13 | P45452 | 5/20 | 0.73 |
| ▸ | MMP8 | P22894 | 2/20 | 0.73 |
| ▸ | MMP2 | P08253 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334839 | 0.84 | ADAM17 (1.00) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL8334970 | 0.82 | ADAM17 (1.00) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL12708189 | 0.82 | ADAM17 (1.00) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL8329165 | 0.82 | ADAM17 (1.00) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL8334567 | 0.81 | ADAM17 (0.77) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL7313611 | 0.81 | ADAM17 (0.65) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL14245317 | 0.79 | ADAM17 (0.63) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL6261997 | 0.77 | ADAM17 (0.61) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL7396462 | 0.77 | ADAM17 (0.65) | ADAM17MMP13MMP8MMP2 | |
| SCHEMBL3940827 | 0.76 | MMP13 (0.80) | ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |