Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17474205 | 0.74 | POLB (0.34) | — | |
| SCHEMBL20811333 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL22221412 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL20811652 | 0.72 | ALDH1A1 (0.32) | ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL2829913 | 0.70 | — | — | |
| SCHEMBL3440469 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL29230313 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL29230314 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL26406136 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL29230339 | 0.67 | ALDH1A1 (0.32) | ALDH1A1MAPTPTGS1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396344-B | One-pot synthetic method for N-t-butyl-aminocarbonyl-3-methyl-L-valine | SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-103396344-B | One-pot synthetic method for N-t-butyl-aminocarbonyl-3-methyl-L-valine | SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |
| EP-2121605-B1 | PROCESS FOR PREPARING (1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-[[[(1,1-DIMETHYLETHYL)AMINO]-CARBONYL]AMINO]-3,3-DIMETHYL-1-OXOBUTYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE | MERCK SHARP & DOHME (US) | 2013-11-20 | — | — | EP | disclosed |
| CN-103396344-A | One-pot synthetic method for N-t-butyl-aminocarbonyl-3-methyl-L-valine | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-11-20 | — | — | CN | disclosed |
| CN-103396344-A | One-pot synthetic method for N-t-butyl-aminocarbonyl-3-methyl-L-valine | SUZHOU UUGENE BIOPHARMA CO LTD | 2013-11-20 | — | — | CN | disclosed |
| US-8163937-B2 | Process for preparing (1R,2S,5S)-N-[(1S)-3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]-carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide | SCHERING CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100145013-A1 | PROCESS FOR PREPARING (1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-[[[(1,1-DIMETHYLETHYL)AMINO]-CARBONYL]AMINO]-3,3-DIMETHYL-1-OXOBUTYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE | SCHERING CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2121605-A1 | PROCESS FOR PREPARING (1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-[[[(1,1-DIMETHYLETHYL)AMINO]-CARBONYL]AMINO]-3,3-DIMETHYL-1-OXOBUTYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE | SCHERING CORPORATION (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008079216-A1 | PROCESS FOR PREPARING (1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-[[[(1,1-DIMETHYLETHYL)AMINO]-CARBONYL]AMINO]-3,3-DIMETHYL-1-OXOBUTYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE | SCHERING CORPORATION (US) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145013-A1 | PROCESS FOR PREPARING (1R,2S,5S)-N-[(1S)-3-AMINO-1-(CYCLOBUTYLMETHYL)-2,3-DIOXOPROPYL]-3-[(2S)-2-[[[(1,1-DIMETHYLETHYL)AMINO]-CARBONYL]AMINO]-3,3-DIMETHYL-1-OXOBUTYL]-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE | CYP1B1, DHPS, AZI2 | ALDH1A1 101/4885MAPT 4326/4885PTGS1 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.