Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 8/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606820 | 1.00 | PYGL (0.45) | PYGLIDO1NAMPTADRB2ADRB1 | |
| SCHEMBL1608870 | 0.87 | PYGL (0.60) | PYGLIDO1 | |
| SCHEMBL12738418 | 0.87 | PYGL (0.60) | PYGLIDO1 | |
| SCHEMBL2107450 | 0.83 | PYGL (0.44) | PYGLNAMPTF9 | |
| SCHEMBL2606821 | 0.80 | PYGL (0.49) | PYGL | |
| SCHEMBL2107472 | 0.79 | PYGL (0.51) | PYGLIDO1NAMPT | |
| SCHEMBL1202395 | 0.76 | MAP2K1 (0.48) | PYGLIDO1 | |
| SCHEMBL14375040 | 0.74 | PYGL (0.37) | PYGLIDO1 | |
| SCHEMBL2106978 | 0.73 | MMP2 (0.39) | PYGLIDO1 | |
| SCHEMBL2106985 | 0.73 | PYGL (0.52) | PYGLITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |