Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 9/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608873 | 0.87 | IDO1 (0.53) | MMP2MMP13MMP14IDO1PDGFRB | |
| SCHEMBL2107451 | 0.83 | MEN1 (0.35) | MMP2MMP13KDM4ELMNATP53 | |
| SCHEMBL2106977 | 0.73 | PYGL (0.45) | IDO1PYGL | |
| SCHEMBL2606820 | 0.73 | PYGL (0.45) | IDO1PYGL | |
| SCHEMBL13271409 | 0.70 | CCNC (0.44) | MMP2MMP13MAP2K1LMNAPYGL | |
| SCHEMBL1202395 | 0.70 | MAP2K1 (0.48) | IDO1MAP2K1L3MBTL1PYGL | |
| SCHEMBL4721594 | 0.68 | CHEK1 (0.44) | IDO1PDGFRBKDM4ELMNAPYGL | |
| SCHEMBL2107472 | 0.67 | PYGL (0.51) | IDO1MAP2K1PYGL | |
| SCHEMBL1202654 | 0.67 | ALOX15 (0.59) | MMP2MMP13MMP14KDM4ELMNA | |
| SCHEMBL31030817 | 0.67 | ALOX15 (0.59) | MMP2MMP13MMP14KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |