Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007427 | 0.97 | GPR119 (0.32) | DGAT1 | |
| SCHEMBL15031505 | 0.91 | — | — | |
| SCHEMBL15007297 | 0.90 | GPR119 (0.33) | DGAT1 | |
| SCHEMBL15026298 | 0.90 | GPR119 (0.33) | DGAT1 | |
| SCHEMBL15007296 | 0.90 | GPR119 (0.33) | DGAT1 | |
| SCHEMBL15007178 | 0.89 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL15026299 | 0.87 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL12503603 | 0.87 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL12503604 | 0.87 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL21073 | 0.83 | GRM4 (0.34) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027236-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |