SCHEMBL2107180

SCHEMBL2107180

CC=C(C(=O)Oc1cc(Oc2ccccc2F)ncn1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.38
RAF1 P04049 2/20 0.38
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
MRGPRX1 Q96LB2 2/20 0.37
MAP4K4 O95819 1/20 0.37
GCK P35557 1/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PARP10 Q53GL7 1/20 0.36
CXCL8 P10145 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450548 0.89 CHRM4 (0.38) MRGPRX4CHRM4GCKFFAR4
SCHEMBL8337946 0.88 SMN1; SMN2 (0.41) KDM4ERAF1MRGPRX1MAP4K4GCK
SCHEMBL8499271 0.84 MAP4K4 (0.39) MAP4K4NPC1RAB9ASMN1; SMN2
SCHEMBL2107519 0.84 KDR (0.32) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL8341502 0.84 HTR2C (0.37) KDM4EMAPTKMT2ANPC1RAB9A
SCHEMBL2852233 0.81 MRGPRX1 (0.40) KDM4ERAF1CHRM2CHRM4CHRM5
SCHEMBL2107178 0.79 KDM4E (0.38) KDM4EMRGPRX4RAF1CHRM2CHRM4
SCHEMBL2107181 0.79 KDM4E (0.38) KDM4EMRGPRX4RAF1CHRM2CHRM4
SCHEMBL2108452 0.78 GCK (0.45) MRGPRX4GCKMEN1KMT2APARP10
SCHEMBL2849776 0.74 GCK (0.38) KDM4EMRGPRX4RAF1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed