Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852233 | 0.93 | MRGPRX1 (0.40) | GCKCHRM4FFAR4KMT2AALDH1A1 | |
| SCHEMBL29362167 | 0.90 | CHRM4 (0.36) | GCKCHRM4FFAR4KDRMAPK14 | |
| SCHEMBL2849774 | 0.90 | CHRM4 (0.36) | GCKCHRM4FFAR4KDRMAPK14 | |
| SCHEMBL2849778 | 0.90 | CHRM4 (0.36) | GCKCHRM4FFAR4KDRMAPK14 | |
| SCHEMBL203207 | 0.84 | GCK (0.38) | GCKCHRM4FFAR4KDRMAPK14 | |
| SCHEMBL2857206 | 0.83 | SMN1; SMN2 (0.44) | KMT2AALDH1A1MRGPRX1KDM4ERAF1 | |
| SCHEMBL2852231 | 0.83 | RAF1 (0.37) | GCKCHRM4FFAR4KDRKMT2A | |
| SCHEMBL2852235 | 0.83 | RAF1 (0.37) | GCKCHRM4FFAR4KDRKMT2A | |
| SCHEMBL29360421 | 0.83 | RAF1 (0.37) | GCKCHRM4FFAR4KDRKMT2A | |
| SCHEMBL203206 | 0.83 | GCK (0.36) | GCKCHRM4KDRMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043600-B2 | Microbiocidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11584740-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-02-21 | — | — | US | disclosed |
| US-11566140-B2 | Exterior coating composition | TROY CORPORATION (US) | 2023-01-31 | — | — | US | disclosed |
| US-11535594-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-12-27 | — | — | US | disclosed |
| EP-3853207-B1 | MICROBIOCIDAL QUINOLINE CARBOXAMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-19 | — | — | EP | disclosed |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | US | disclosed |
| US-6893651-B1 | Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-17 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040127520-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2004-07-01 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5972971-A | WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | GCK 4495/4885CHRM4 9/4885FFAR4 1612/4885 |
| US-12043600-B2 | Microbiocidal compounds | MPO, MSR1, PRF1 | GCK 2373/4885CHRM4 734/4885FFAR4 1066/4885 |
| US-20040127520-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | GCK 4495/4885CHRM4 9/4885FFAR4 1612/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | GCK 1898/4885CHRM4 1096/4885FFAR4 1097/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | GCK 695/4885CHRM4 2608/4885FFAR4 1747/4885 |
| US-20050187215-A1 | synergistic mixture of certain previously disclosed cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors | CHRNG, CHRM3, CHRNE | GCK 2834/4885CHRM4 14/4885FFAR4 315/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | GCK 3426/4885CHRM4 1592/4885FFAR4 513/4885 |
| US-11535594-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | GCK 3426/4885CHRM4 1592/4885FFAR4 513/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | GCK 968/4885CHRM4 3687/4885FFAR4 2000/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | GCK 3365/4885CHRM4 1552/4885FFAR4 518/4885 |
| US-11584740-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | IFNG, TLR1, IDO1 | GCK 1212/4885CHRM4 2108/4885FFAR4 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.