SCHEMBL21074288

SCHEMBL21074288

Cc1ccc2c(oc3ccccc32)c1N1c2ccccc2N(C(C)C)C1C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CYP2C19 P33261 1/20 0.32
PGR P06401 1/20 0.32
HTT P42858 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349238 1.00 MEN1 (0.32) MEN1KMT2ACYP2C19PGRHTT
SCHEMBL16716690 1.00 MEN1 (0.32) MEN1KMT2ACYP2C19PGRHTT
SCHEMBL16727574 0.93 PGR (0.32) MEN1KMT2ACYP2C19PGR
SCHEMBL16716727 0.88 PRKDC (0.30)
SCHEMBL16726501 0.88 MEN1 (0.32) MEN1KMT2ACYP2C19PGR
SCHEMBL21468819 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL21074296 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL20349239 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL16716728 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL20349241 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 US disclosed
EP-3492480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-20 EP disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 MEN1 989/4885KMT2A 3940/4885CYP2C19 1068/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP MEN1 1965/4885KMT2A 3332/4885CYP2C19 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.