SCHEMBL16716690

SCHEMBL16716690

Cc1ccc2c(oc3ccccc32)c1N1c2ccccc2N(C(C)C)[C@H]1C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CYP2C19 P33261 1/20 0.32
PGR P06401 1/20 0.32
HTT P42858 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349238 1.00 MEN1 (0.32) MEN1KMT2ACYP2C19PGRHTT
SCHEMBL21074288 1.00 MEN1 (0.32) MEN1KMT2ACYP2C19PGRHTT
SCHEMBL16727574 0.93 PGR (0.32) MEN1KMT2ACYP2C19PGR
SCHEMBL16716727 0.88 PRKDC (0.30)
SCHEMBL16726501 0.88 MEN1 (0.32) MEN1KMT2ACYP2C19PGR
SCHEMBL21468819 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL21074296 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL20349239 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL16716728 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1
SCHEMBL20349241 0.87 TSHR (0.33) MEN1KMT2ACYP2C19HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3220441-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-04-22 EP disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 US disclosed
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-03-29 US disclosed
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
EP-3220440-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-09-20 EP disclosed
EP-2874192-B1 Organic eletroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-10 EP disclosed
EP-2874195-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-03 EP disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137095-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
US-20150137095-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 US disclosed
EP-2874195-A2 Organic eletroluminescent materials and devices Universal Display Corporation (US) 2015-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10033000-B2 Organic electroluminescent materials and devices LSM8, OPRM1, OXER1 MEN1 2405/4885KMT2A 2973/4885CYP2C19 3309/4885
US-20180090691-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, TYR, CPNE4 MEN1 1904/4885KMT2A 1268/4885CYP2C19 1001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.