Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA1 | P00915 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556468 | 0.82 | MAPT (0.31) | — | |
| SCHEMBL19849318 | 0.81 | ALDH1A1 (0.34) | EPHX1MEN1KMT2A | |
| SCHEMBL20663679 | 0.80 | ACHE (0.41) | EPHX1MEN1KMT2A | |
| SCHEMBL19849316 | 0.79 | ACHE (0.39) | MEN1KMT2A | |
| SCHEMBL16865195 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL19849305 | 0.78 | MEN1 (0.44) | EPHX1MEN1KMT2A | |
| SCHEMBL19849335 | 0.77 | — | — | |
| SCHEMBL19849322 | 0.76 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL21074501 | 0.76 | ACHE (0.41) | MEN1KMT2A | |
| SCHEMBL7109697 | 0.76 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | IVOCLAR VIVADENT AG (LI) | 2021-10-05 | — | — | US | disclosed |
| US-10660825-B2 | — | — | 2020-05-26 | — | — | US | disclosed |
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | RAD51, CBR1, DECR1 | IDO1 4712/4885CA12 1631/4885CA1 497/4885 |
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | RAD51, CBR1, DECR1 | IDO1 4712/4885CA12 1631/4885CA1 497/4885 |
| US-10660825-B2 | — | OXER1, CBR1, RAD51 | IDO1 4146/4885CA12 2117/4885CA1 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.