Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.83 |
| ▸ | DRD2 | P14416 | 11/20 | 0.83 |
| ▸ | HTR2C | P28335 | 7/20 | 0.81 |
| ▸ | HTR7 | P34969 | 3/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.81 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.81 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.81 |
| ▸ | DRD1 | P21728 | 2/20 | 0.81 |
| ▸ | DRD4 | P21917 | 2/20 | 0.81 |
| ▸ | DRD5 | P21918 | 2/20 | 0.81 |
| ▸ | HTR1D | P28221 | 2/20 | 0.81 |
| ▸ | HTR1B | P28222 | 2/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.81 |
| ▸ | HRH1 | P35367 | 2/20 | 0.81 |
| ▸ | DRD3 | P35462 | 2/20 | 0.81 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.81 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.81 |
| ▸ | ACHE | P22303 | 3/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489409 | 0.94 | HTR2A (0.80) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL7348719 | 0.93 | DRD2 (0.78) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL14068778 | 0.91 | DRD2 (0.76) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL30618926 | 0.91 | DRD2 (0.76) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL7382834 | 0.91 | HTR2A (0.80) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL801449 | 0.91 | DRD2 (0.85) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL7299943 | 0.90 | DRD2 (0.80) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| Paliperidone SCHEMBL20572022 | 0.90 | DRD2 (1.00) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| Paliperidone SCHEMBL436689 | 0.90 | DRD2 (1.00) | HTR2ADRD2HTR2CHTR7KCNH2 | |
| SCHEMBL17245287 | 0.90 | DRD2 (0.84) | HTR2ADRD2HTR2CHTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556759-B1 | HAPTENS OF PALIPERIDONE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-29 | — | — | EP | disclosed |
| EP-2888258-B1 | HAPTENS OF PALIPERIDONE | JANSSEN PHARMACEUTICA NV (BE) | 2019-06-05 | — | — | EP | disclosed |