Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA6 | P23280 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CASP2 | P42575 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292581 | 0.93 | CA12 (0.46) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21982018 | 0.92 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21164243 | 0.92 | CA12 (0.43) | CA12CA6CA7CA9CA14 | |
| SCHEMBL14413917 | 0.91 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8863209 | 0.87 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL24175702 | 0.86 | LMNA (0.43) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21799519 | 0.85 | CA12 (0.42) | CA12CA6CA7CA9CA14 | |
| SCHEMBL198494 | 0.84 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL22166080 | 0.84 | CA12 (0.59) | CA12CA6CA7CA9CA14 | |
| SCHEMBL21164235 | 0.84 | CA12 (0.42) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178828-B1 | ALDIMINES AND COMPOUNDS CONTAINING ALDIMINE | SIKA TECH AG (CH) | 2019-06-26 | — | — | EP | disclosed |
| EP-2132248-B1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| US-8455100-B2 | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG (CH) | 2013-06-04 | — | — | US | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-8252859-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2012-08-28 | — | — | US | disclosed |
| US-8157950-B2 | Aldimine and composition containing aldimine | SIKA TECHNOLOGY AG (CH) | 2012-04-17 | — | — | US | disclosed |
| US-20110253309-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-10-20 | — | — | US | disclosed |
| EP-2194082-B1 | Aldimine and composition comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2011-09-07 | — | — | EP | disclosed |
| EP-2200973-B1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-07-13 | — | — | EP | disclosed |
| WO-2009080738-A1 | CURABLE COMPOSITIONS HAVING LESS VOLATILIZATION | SIKA TECHNOLOGY AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| EP-2072550-A1 | Hardening compounds with reduced gas emission | Sika Technology AG (CH) | 2009-06-24 | — | — | EP | disclosed |
| WO-2009027511-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | disclosed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | disclosed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1934169-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1772447-A1 | Aldimines with reactive groups comprising active hydrogen, and their use | Sika Technology AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2007036571-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | CA12 2380/4885CA6 3222/4885CA7 2527/4885 |
| US-20110253309-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | ALDH7A1, ALDH3A1, ADH5 | CA12 1993/4885CA6 2190/4885CA7 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.