Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17837270 | 0.84 | BUB1 (0.34) | BUB1BCHEELANE | |
| SCHEMBL17837259 | 0.78 | USP30 (0.40) | BUB1 | |
| SCHEMBL21075867 | 0.77 | — | — | |
| SCHEMBL17873707 | 0.74 | CDC7 (0.35) | BUB1 | |
| SCHEMBL17837206 | 0.73 | MAPK3 (0.37) | — | |
| SCHEMBL24837240 | 0.69 | — | — | |
| SCHEMBL30900413 | 0.69 | ELANE (0.33) | BUB1ELANE | |
| SCHEMBL25234196 | 0.68 | CDK1 (0.39) | BUB1 | |
| SCHEMBL17141679 | 0.68 | CDK1 (0.39) | BUB1 | |
| SCHEMBL30900373 | 0.67 | RORC (0.33) | BUB1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237423-B1 | THIENO[2,3-C]PYRROL-4-ONE DERIVATIVES AS ERK INHIBITORS | LILLY CO ELI (US) | 2019-06-05 | — | — | EP | disclosed |