Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768422 | 0.88 | HTT (0.52) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL18250215 | 0.81 | ALDH1A1 (0.46) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL17124776 | 0.79 | ALDH1A1 (0.44) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL14768424 | 0.78 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL21076157 | 0.73 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL17124779 | 0.71 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1PTGDR2 | |
| SCHEMBL11000898 | 0.71 | GAA (0.57) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL3732393 | 0.71 | ALDH1A1 (0.57) | HTTNPC1ALDH1A1MAPTGAA | |
| SCHEMBL17124777 | 0.70 | JAK2 (0.55) | LMNAHTTNPC1ALDH1A1MAPT | |
| SCHEMBL17130188 | 0.70 | L3MBTL1 (0.47) | LMNAALDH1A1L3MBTL1HSD17B10PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753599-B1 | BIPHENYL COMPOUNDS FOR USE IN TREATING MALARIA AND OTHER PARASITIC DISORDERS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2019-06-05 | — | — | EP | disclosed |