Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 6/20 | 0.34 |
| ▸ | GCK | P35557 | 4/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076983 | 0.79 | GCK (0.32) | GCKTMIGD3ADORA1 | |
| SCHEMBL21077015 | 0.77 | CTPS1 (0.41) | POLBGCKADRB3 | |
| SCHEMBL21077199 | 0.76 | CTPS1 (0.53) | ADRB3ALDH1A1 | |
| SCHEMBL21387648 | 0.75 | CTPS1 (0.38) | — | |
| SCHEMBL21044216 | 0.75 | CTPS1 (0.46) | GCK | |
| SCHEMBL21077147 | 0.74 | CTPS1 (0.54) | POLBADRB3 | |
| SCHEMBL21076846 | 0.74 | ALDH1A1 (0.44) | PDE5AALDH1A1 | |
| SCHEMBL5627029 | 0.73 | POLB (0.40) | POLBPDE5ACCR2ALDH1A1 | |
| SCHEMBL22762267 | 0.72 | — | — | |
| SCHEMBL21077072 | 0.71 | ALDH1A1 (0.50) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |