Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077072 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL21076989 | 0.80 | GAA (0.51) | ALDH1A1GAAMAPTNPC1NFKB1 | |
| SCHEMBL21077075 | 0.78 | CTPS1 (0.64) | GAAMAPTLMNASMN1; SMN2CTPS1 | |
| SCHEMBL21077101 | 0.77 | CTPS1 (0.53) | MAPTLMNAKDM4ESMN1; SMN2CTPS1 | |
| SCHEMBL21077128 | 0.76 | CTPS1 (0.67) | KDM4ECTPS1PDE5A | |
| SCHEMBL21077035 | 0.75 | CTPS1 (0.52) | ALDH1A1GAAMAPTLMNAHPGD | |
| SCHEMBL21077246 | 0.75 | CTPS1 (0.54) | GAAMAPTLMNASMN1; SMN2CTPS1 | |
| SCHEMBL21076840 | 0.74 | POLB (0.36) | ALDH1A1PDE5A | |
| SCHEMBL21076844 | 0.71 | CTPS1 (0.65) | ALDH1A1GAAMAPTNPC1NFKB1 | |
| SCHEMBL21044274 | 0.69 | CTPS1 (0.59) | ALDH1A1GAAMAPTNPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |