Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 9/20 | 0.57 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077128 | 0.92 | CTPS1 (0.67) | CTPS1WNT3A | |
| SCHEMBL21076999 | 0.89 | CTPS1 (0.68) | CTPS1WNT3A | |
| SCHEMBL21077150 | 0.84 | CTPS1 (0.51) | CTPS1ALDH1A1HTTMAPT | |
| SCHEMBL21077093 | 0.83 | CTPS1 (0.55) | CTPS1WNT3AGSK3BDYRK1AABL1 | |
| SCHEMBL32663036 | 0.81 | CTPS1 (0.85) | CTPS1 | |
| SCHEMBL21044320 | 0.81 | CTPS1 (0.85) | CTPS1 | |
| SCHEMBL21076939 | 0.80 | CTPS1 (0.51) | CTPS1MAPT | |
| SCHEMBL21077018 | 0.80 | CTPS1 (0.53) | CTPS1WNT3A | |
| SCHEMBL21077075 | 0.80 | CTPS1 (0.64) | CTPS1WNT3AHTTMAPT | |
| SCHEMBL21077246 | 0.79 | CTPS1 (0.54) | CTPS1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |