Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 7/20 | 0.67 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.42 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076877 | 0.92 | CTPS1 (0.57) | CTPS1WNT3A | |
| SCHEMBL21076939 | 0.83 | CTPS1 (0.51) | CTPS1MEN1KMT2A | |
| SCHEMBL21076999 | 0.83 | CTPS1 (0.68) | CTPS1WNT3A | |
| SCHEMBL31152540 | 0.80 | CTPS1 (1.00) | CTPS1WNT3A | |
| SCHEMBL21044051 | 0.80 | CTPS1 (1.00) | CTPS1WNT3A | |
| SCHEMBL21077075 | 0.80 | CTPS1 (0.64) | CTPS1WNT3AMEN1KMT2A | |
| SCHEMBL21077246 | 0.79 | CTPS1 (0.54) | CTPS1MEN1KMT2A | |
| SCHEMBL21077101 | 0.79 | CTPS1 (0.53) | CTPS1MEN1KMT2AKDM4E | |
| SCHEMBL21077035 | 0.77 | CTPS1 (0.52) | CTPS1MEN1KMT2A | |
| SCHEMBL21077018 | 0.76 | CTPS1 (0.53) | CTPS1WNT3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |