Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 11/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076999 | 0.87 | CTPS1 (0.68) | CTPS1PORCN | |
| SCHEMBL21077075 | 0.87 | CTPS1 (0.64) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21077246 | 0.86 | CTPS1 (0.54) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21077035 | 0.86 | CTPS1 (0.52) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21077101 | 0.86 | CTPS1 (0.53) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21077018 | 0.83 | CTPS1 (0.53) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21077128 | 0.83 | CTPS1 (0.67) | CTPS1MEN1KMT2A | |
| SCHEMBL21044528 | 0.81 | CTPS1 (0.77) | CTPS1 | |
| SCHEMBL21076877 | 0.80 | CTPS1 (0.57) | CTPS1MAPT | |
| SCHEMBL21077007 | 0.80 | L3MBTL1 (0.51) | CTPS1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |