Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 11/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077075 | 0.89 | CTPS1 (0.64) | CTPS1LMNAHTTMEN1KMT2A | |
| SCHEMBL21077101 | 0.88 | CTPS1 (0.53) | CTPS1LMNAHTTMEN1KMT2A | |
| SCHEMBL21077246 | 0.86 | CTPS1 (0.54) | CTPS1LMNAHTTMEN1KMT2A | |
| SCHEMBL21076939 | 0.86 | CTPS1 (0.51) | CTPS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21076999 | 0.84 | CTPS1 (0.68) | CTPS1 | |
| SCHEMBL21077007 | 0.83 | L3MBTL1 (0.51) | CTPS1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL21077018 | 0.81 | CTPS1 (0.53) | CTPS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL21044278 | 0.81 | CTPS1 (0.79) | CTPS1 | |
| SCHEMBL21077154 | 0.81 | CTPS1 (0.46) | CTPS1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL21076846 | 0.75 | ALDH1A1 (0.44) | CTPS1LMNAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |