Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 7/20 | 0.44 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044407 | 0.85 | CTPS1 (0.61) | CTPS1CTPS2F10AKT1PIK3CA | |
| SCHEMBL30528879 | 0.85 | CTPS1 (0.61) | CTPS1CTPS2F10AKT1PIK3CA | |
| SCHEMBL21077153 | 0.84 | CTPS1 (0.46) | CTPS1CTPS2 | |
| SCHEMBL21076934 | 0.84 | CTPS1 (0.45) | CTPS1CTPS2 | |
| SCHEMBL21077188 | 0.84 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL21077093 | 0.82 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21077203 | 0.81 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL21077165 | 0.80 | CTPS1 (0.47) | CTPS1CTPS2 | |
| SCHEMBL21076941 | 0.79 | CTPS1 (0.50) | CTPS1CTPS2 | |
| SCHEMBL21076932 | 0.79 | CTPS1 (0.52) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |