Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691092 | 0.70 | LPL (0.50) | LPLLIPGROCK1 | |
| SCHEMBL21245708 | 0.69 | CSF1R (0.37) | LPLLIPGROCK1 | |
| SCHEMBL19804941 | 0.67 | LPL (0.41) | LPLLIPGROCK1 | |
| SCHEMBL14956694 | 0.67 | LPL (0.43) | LPLLIPGROCK1 | |
| SCHEMBL24632979 | 0.66 | ROCK1 (0.33) | LPLLIPGROCK1 | |
| SCHEMBL21245840 | 0.66 | CDK4 (0.39) | — | |
| SCHEMBL22357671 | 0.66 | ROCK1 (0.37) | LPLLIPGROCK1BACE1 | |
| SCHEMBL30748768 | 0.66 | IRAK4 (0.36) | LPLLIPGROCK1 | |
| SCHEMBL16535308 | 0.65 | LPL (0.42) | LPLLIPGROCK1 | |
| SCHEMBL17421129 | 0.65 | LPL (0.42) | LPLLIPGROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492462-B1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | SHENZHEN TARGETRX INC (CN) | 2023-08-30 | — | — | EP | disclosed |
| EP-3492462-A1 | AMINO PYRIMIDINE COMPOUND FOR INHIBITING PROTEIN TYROSINE KINASE ACTIVITY | Shenzhen Targetrx, Inc. (CN) | 2019-06-05 | — | — | EP | disclosed |