Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22357680 | 0.82 | CSF1R (0.32) | — | |
| SCHEMBL20865747 | 0.73 | LPL (0.37) | ROCK1LPLLIPG | |
| SCHEMBL31394505 | 0.73 | LPL (0.39) | ROCK1LPLLIPG | |
| SCHEMBL15288616 | 0.72 | LIPG (0.40) | ROCK1LPLLIPGBACE1BACE2 | |
| SCHEMBL21493489 | 0.71 | KIF11 (0.39) | ROCK1LPLLIPGBACE1 | |
| SCHEMBL17419176 | 0.71 | ROCK1 (0.37) | ROCK1LPLLIPG | |
| SCHEMBL4998784 | 0.70 | LPL (0.39) | ROCK1LPLLIPG | |
| SCHEMBL18530177 | 0.69 | MAPK1 (0.39) | ROCK1LPLLIPG | |
| SCHEMBL530658 | 0.69 | LPL (0.47) | ROCK1LPLLIPGF11 | |
| SCHEMBL6691092 | 0.69 | LPL (0.50) | ROCK1LPLLIPGF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532476-B1 | FUSED AZAHETEROCYCLIC COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-19 | — | — | EP | disclosed |