SCHEMBL30748768

SCHEMBL30748768

CC(C)n1ncc2cc(B3OC(C)(C)C(C)(C)O3)cc(F)c21

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.36
LPL P06858 2/20 0.35
LIPG Q9Y5X9 2/20 0.35
FFAR1 O14842 1/20 0.35
ROCK1 Q13464 1/20 0.32
AAK1 Q2M2I8 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
PDE1A P54750 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE1C Q14123 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30754789 0.83 IRAK4 (0.38) IRAK4LPLLIPGFFAR1ROCK1
SCHEMBL21871228 0.83 IRAK4 (0.38) IRAK4LPLLIPGFFAR1ROCK1
SCHEMBL20719723 0.80 IRAK4 (0.36) IRAK4LPLLIPGFFAR1ROCK1
SCHEMBL15661436 0.77 IRAK4 (0.47) IRAK4LPLLIPGFFAR1IDO1
SCHEMBL31221824 0.77 ADORA3 (0.38) IRAK4LPLLIPGFFAR1AAK1
SCHEMBL30551179 0.77 IRAK4 (0.47) IRAK4LPLLIPGFFAR1IDO1
SCHEMBL25290275 0.75 LPL (0.34) LPLLIPGFFAR1
SCHEMBL30381461 0.74 IRAK4 (0.56) IRAK4LPLLIPGFFAR1IDO1
SCHEMBL15661832 0.74 IRAK4 (0.56) IRAK4LPLLIPGFFAR1IDO1
SCHEMBL21929907 0.73 IRAK4 (0.35) IRAK4LPLLIPGFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT IRAK4 3322/4885LPL 360/4885LIPG 497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.