SCHEMBL2107767

SCHEMBL2107767

CC(=O)Cc1ccc2c(Cl)ccc(OOC(C)=O)c2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX12 P18054 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PDE4A P27815 2/20 0.36
PDE4B Q07343 2/20 0.36
PDE4C Q08493 2/20 0.36
PDE4D Q08499 2/20 0.36
PKM P14618 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.34
HTT P42858 2/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28362662 0.88 PDE4B (0.47) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL28907563 0.84 KDM4E (0.41) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL28884125 0.81 KDM4E (0.45) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL342126 0.81 KDM4E (0.45) KDM4ECYP3A4ALOX12TDP1PDE4D
SCHEMBL19520370 0.78 KDM4E (0.37) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL6348670 0.74 PDE4B (0.48) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL4180590 0.73 KDM4E (0.74) KDM4ECYP3A4ALOX12TDP1PKM
SCHEMBL16132605 0.73 PDE4B (0.47) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL2107275 0.72 KDM4E (0.36) KDM4ECYP3A4ALOX12TDP1PDE4A
SCHEMBL30515497 0.72 KDM4E (0.36) KDM4ECYP3A4ALOX12TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2026-05-28 US disclosed
CN-114401956-A Substituted N-phenyluracils, their salts and their use as herbicides 拜耳公司 2022-04-26 CN disclosed
WO-2017186577-A1 TIMED-RELEASE-TYPE GRANULAR AGROCHEMICAL COMPOSITION AND METHOD FOR MANUFACTURING SAME BAYER CROPSCIENCE AKTIENGESSELSCHAFT (DE) 2017-11-02 WO disclosed
US-8158558-B2 Synergistic mixture of a mesosulfuron or iodinosulfuron ester of given formula, with another herbicide selected from a list of 23 that includes picolinafen, flucarbazone, procarbazone and cinidon-ethyl; controlling weeds in monocot crops BAYER CROPSCIENCE GMBH (DE) 2012-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144250-A1 SOLVENT-FREE FORMULATIONS OF LOW-MELTING ACTIVE INGREDIENTS FOXM1, CSDE1, RCC1 KDM4E 1585/4885CYP3A4 304/4885ALOX12 1066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.