Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342560 | 0.87 | KDM4E (0.47) | KDM4EPKMHTTL3MBTL1TDP1 | |
| SCHEMBL3609400 | 0.83 | KDM4E (0.41) | KDM4EPKMHTTTDP1CYP3A4 | |
| SCHEMBL2107767 | 0.81 | KDM4E (0.44) | KDM4EPKMHTTL3MBTL1TDP1 | |
| SCHEMBL3988279 | 0.81 | TDP1 (0.47) | KDM4EPKMHTTTDP1TSHR | |
| SCHEMBL341040 | 0.76 | PTGDR (0.40) | KDM4EPKMHTTTDP1CYP3A4 | |
| SCHEMBL339944 | 0.75 | KDM4E (0.43) | KDM4EPKMHTTTDP1CYP3A4 | |
| SCHEMBL29490828 | 0.73 | PKM (0.71) | KDM4EPKMHTTL3MBTL1TDP1 | |
| SCHEMBL137002 | 0.73 | PKM (0.71) | KDM4EPKMHTTL3MBTL1TDP1 | |
| SCHEMBL9618459 | 0.72 | KDM4E (0.39) | KDM4EPKMHTTL3MBTL1TDP1 | |
| SCHEMBL7187750 | 0.72 | PKM (0.70) | KDM4EPKMHTTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | claimed |
| EP-1989162-B1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-07-03 | — | — | EP | claimed |
| US-20080188371-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | US | claimed |
| US-20080026943-A1 | Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-01-31 | — | — | US | claimed |
| US-20070298969-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFF (DE) | 2007-12-27 | — | — | US | claimed |
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2007-10-18 | — | — | US | claimed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | claimed |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | claimed |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | BAYER CROPSCIENCE AG (DE) | 2007-04-26 | — | — | US | claimed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | claimed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | KDM4E 2418/4885PKM 928/4885HTT 117/4885 |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | DDT, CYP4X1, HPD | KDM4E 402/4885PKM 1033/4885HTT 2910/4885 |
| US-20070244007-A1 | Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives | AGXT, PAOX, DDT | KDM4E 3547/4885PKM 366/4885HTT 1003/4885 |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | DDT, DDC, DAO | KDM4E 837/4885PKM 121/4885HTT 608/4885 |
| US-20080188371-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | KDM4E 497/4885PKM 628/4885HTT 3172/4885 |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | KDM4E 4013/4885PKM 649/4885HTT 302/4885 |
| US-20070298969-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Spirocyclic Tetramic Acid Derivatives | DDT, PKD2, CYP2D6 | KDM4E 1986/4885PKM 69/4885HTT 145/4885 |
| US-20080026943-A1 | Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives | DDT, CYP1A1, CYP1B1 | KDM4E 848/4885PKM 1046/4885HTT 3060/4885 |
| US-20070225170-A1 | 2-Halo-6-Alkylphenyl-Substituted Tetramic Acid Derivatives | DDT, HDHD5, TBCA | KDM4E 3947/4885PKM 728/4885HTT 203/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | KDM4E 2868/4885PKM 306/4885HTT 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.