Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29090112 | 0.81 | DRD2 (0.72) | CCR3DRD2OPRL1OPRM1OPRD1 | |
| SCHEMBL21078157 | 0.81 | OPRM1 (0.55) | DRD2OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11205205 | 0.81 | CCR3 (0.57) | CCR3DRD2OPRL1OPRM1OPRD1 | |
| SCHEMBL3591423 | 0.81 | CCR3 (0.57) | CCR3DRD2OPRL1OPRM1OPRD1 | |
| SCHEMBL21077856 | 0.81 | OPRM1 (0.55) | DRD2OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL3591425 | 0.81 | CCR3 (0.57) | CCR3DRD2OPRL1OPRM1OPRD1 | |
| SCHEMBL21077875 | 0.80 | OPRL1 (0.47) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL21077926 | 0.80 | OPRL1 (0.58) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL14307260 | 0.79 | CCR3 (0.69) | CCR3DRD2OPRL1OPRM1ADRA1A | |
| SCHEMBL21078101 | 0.79 | OPRL1 (0.52) | CCR3DRD2OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041841-B1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2019-06-05 | — | — | EP | disclosed |