SCHEMBL21078201

SCHEMBL21078201

Cc1cc(Cl)ccc1/N=C(\c1ccccc1)c1cccc(/C(=N/c2ccc(Cl)cc2C)c2ccccc2)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 3/20 0.38
ESR2 Q92731 3/20 0.38
ESR1 P03372 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KMT2A Q03164 2/20 0.38
GFER P55789 1/20 0.38
GRM2 Q14416 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
NPFFR1 Q9GZQ6 1/20 0.35
NPFFR2 Q9Y5X5 1/20 0.35
S100B P04271 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5587353 0.86 KMT2A (0.41) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL19887500 0.86 KMT2A (0.41) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL5588691 0.84 KMT2A (0.40) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL25876650 0.83 SIGMAR1 (0.43) ESR2ESR1SMN1; SMN2ALDH1A1MAPT
SCHEMBL5588070 0.82 ESR2 (0.56) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL14280806 0.82 ESR2 (0.56) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL19891798 0.81 LMNA (0.42) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL5588553 0.81 ESR2 (0.54) ESR2ESR1SMN1; SMN2KMT2AALDH1A1
SCHEMBL21078307 0.81 ESR1 (0.38) MRGPRX4ESR2ESR1SMN1; SMN2KMT2A
SCHEMBL23982592 0.80 KMT2A (0.35) ESR2ESR1SMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed
US-10926250-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-23 US disclosed
US-20210023540-A1 Catalyst Systems and Polymerization Processes for Using the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-01-28 US disclosed
US-20190168203-A1 Catalyst Systems and Polymerization Processes for Using the Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-06-06 US disclosed