Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESD | P10768 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19866237 | 0.92 | SMN1; SMN2 (0.52) | ESDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL19866194 | 0.88 | SMN1; SMN2 (0.46) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL19866337 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2PRKCZLMNAMEN1 | |
| SCHEMBL19866328 | 0.83 | ESD (0.49) | ESDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL22795865 | 0.83 | ESD (0.55) | ESDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL19866240 | 0.81 | ESD (0.53) | ESDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL19866263 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL19866299 | 0.77 | ESD (0.42) | ESDALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL19866264 | 0.77 | MAOB (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL19866192 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166840-A1 | SUBSTITUTED PYRAZOLINYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | HPD, GMDS, WEE1 | ESD 1602/4885ALDH1A1 947/4885KDM4E 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.