Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ASPH | Q12797 | 2/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21078911 | 0.84 | KDM4E (0.37) | MAPTKDM4EASPHKDM8TSHR | |
| SCHEMBL15350374 | 0.84 | ASPH (0.41) | KDM4EASPHKDM8TSHRP4HTM | |
| SCHEMBL15350397 | 0.81 | KDM4E (0.40) | MAPTKDM4EASPHKDM8TSHR | |
| SCHEMBL15350001 | 0.80 | ASPH (0.46) | KDM4EASPHKDM8L3MBTL1CNR2 | |
| SCHEMBL15350838 | 0.79 | ASPH (0.42) | KDM4EASPHKDM8L3MBTL1MAPK1 | |
| SCHEMBL31032278 | 0.76 | KDM4E (0.41) | KDM4EASPHKDM8P4HTML3MBTL1 | |
| SCHEMBL29272155 | 0.76 | KDM4E (0.41) | KDM4EASPHKDM8P4HTML3MBTL1 | |
| SCHEMBL15351261 | 0.76 | KMO (0.48) | CNR2 | |
| SCHEMBL15349985 | 0.76 | KMT2A (0.40) | MAPTKDM4EASPHKDM8L3MBTL1 | |
| SCHEMBL15350118 | 0.76 | FFAR4 (0.51) | MAPTP4HTMMRGPRX4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841421-B1 | AMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-06-05 | — | — | EP | disclosed |